Quantitative Degradomics Analysis of Proteolytic Post - Translational Modifications of the Cancer Proteome
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منابع مشابه
Metadegradomics: toward in vivo quantitative degradomics of proteolytic post-translational modifications of the cancer proteome.
Post-translational modifications enable extra layers of control of the proteome, and perhaps the most important is proteolysis, a major irreversible modification affecting every protein. The intersection of the protease web with a proteome sculpts that proteome, dynamically modifying its state and function. Protease expression is distorted in cancer, so perturbing signaling pathways and the sec...
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